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SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT

Malignant phyllodes tumors (MPT) of the breast are rare, and spinal metastasis from these tumors is even rarer. We present a case report of a 37-year-old female with a breast mass, who was diagnosed with malignant MPT after incisional biopsy. The patient underwent a right partial mastectomy, and neg...

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Autores principales: Xavier, Rutayisire François, Claire, Karekezi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616618/
http://dx.doi.org/10.1093/noajnl/vdad121.052
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author Xavier, Rutayisire François
Claire, Karekezi
author_facet Xavier, Rutayisire François
Claire, Karekezi
author_sort Xavier, Rutayisire François
collection PubMed
description Malignant phyllodes tumors (MPT) of the breast are rare, and spinal metastasis from these tumors is even rarer. We present a case report of a 37-year-old female with a breast mass, who was diagnosed with malignant MPT after incisional biopsy. The patient underwent a right partial mastectomy, and negative margins were reported. However, two weeks later, the patient presented to the emergency department with severe back pain, paresthesia, and lower limb weakness. Neurosurgery consultation led to a diagnosis of T4 pathological fracture, spinal tumor and spinal cord compression, likely due to metastasis from the breast mass. Chest abdomen and pelvis CT revealed no other lesion except the T4 compression fracture. The patient underwent cord decompression tumor resection, and transpedicular fixation of T3-T5 with T4 vertebroplasty. Histopathological analysis confirmed that it was a metastasis from phyllodes tumor. Our case report highlights the importance of early detection and management of MPT, as well as the need for close follow-up and monitoring of patients with a history of breast masses it also highlights the importance of considering malignant phyllodes tumors as a differential diagnosis for breast masses and the potential for metastasis to the spine.
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spelling pubmed-106166182023-11-01 SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT Xavier, Rutayisire François Claire, Karekezi Neurooncol Adv Final Category: Spinal Tumors Malignant phyllodes tumors (MPT) of the breast are rare, and spinal metastasis from these tumors is even rarer. We present a case report of a 37-year-old female with a breast mass, who was diagnosed with malignant MPT after incisional biopsy. The patient underwent a right partial mastectomy, and negative margins were reported. However, two weeks later, the patient presented to the emergency department with severe back pain, paresthesia, and lower limb weakness. Neurosurgery consultation led to a diagnosis of T4 pathological fracture, spinal tumor and spinal cord compression, likely due to metastasis from the breast mass. Chest abdomen and pelvis CT revealed no other lesion except the T4 compression fracture. The patient underwent cord decompression tumor resection, and transpedicular fixation of T3-T5 with T4 vertebroplasty. Histopathological analysis confirmed that it was a metastasis from phyllodes tumor. Our case report highlights the importance of early detection and management of MPT, as well as the need for close follow-up and monitoring of patients with a history of breast masses it also highlights the importance of considering malignant phyllodes tumors as a differential diagnosis for breast masses and the potential for metastasis to the spine. Oxford University Press 2023-10-31 /pmc/articles/PMC10616618/ http://dx.doi.org/10.1093/noajnl/vdad121.052 Text en © The Author(s) 2023. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Final Category: Spinal Tumors
Xavier, Rutayisire François
Claire, Karekezi
SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title_full SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title_fullStr SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title_full_unstemmed SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title_short SPINAL TUMORS-03 MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH METASTASIS TO THE THORACIC SPINE: A CASE REPORT
title_sort spinal tumors-03 malignant phyllodes tumor of the breast with metastasis to the thoracic spine: a case report
topic Final Category: Spinal Tumors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616618/
http://dx.doi.org/10.1093/noajnl/vdad121.052
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