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Protein quality assessment with a loss function designed for high-quality decoys

Motivation: The prediction of a protein 3D structure is essential for understanding protein function, drug discovery, and disease mechanisms; with the advent of methods like AlphaFold that are capable of producing very high-quality decoys, ensuring the quality of those decoys can provide further con...

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Detalles Bibliográficos
Autores principales: Roy, Soumyadip, Ben-Hur, Asa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616882/
https://www.ncbi.nlm.nih.gov/pubmed/37915563
http://dx.doi.org/10.3389/fbinf.2023.1198218