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Heterogeneity of surrogate outcome measures used in critical care studies: A systematic review

BACKGROUND: The choice of outcome measure is a critical decision in the design of any clinical trial, but many Phase III clinical trials in critical care fail to detect a difference between the interventions being compared. This may be because the surrogate outcomes used to show beneficial effects i...

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Detalles Bibliográficos
Autores principales:	Verghis, Rejina, Blackwood, Bronagh, McDowell, Cliona, Toner, Philip, Hadfield, Daniel, Gordon, Anthony C, Clarke, Mike, McAuley, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617004/ https://www.ncbi.nlm.nih.gov/pubmed/36946422 http://dx.doi.org/10.1177/17407745231151842

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