Cargando…

Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection

PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implanta...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Yi, Wang, Xuefei, Chen, Liangwan, Wu, Qingsong, Li, Qianzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617069/
https://www.ncbi.nlm.nih.gov/pubmed/37907843
http://dx.doi.org/10.1186/s12872-023-03513-3
_version_ 1785129524677050368
author Dong, Yi
Wang, Xuefei
Chen, Liangwan
Wu, Qingsong
Li, Qianzhen
author_facet Dong, Yi
Wang, Xuefei
Chen, Liangwan
Wu, Qingsong
Li, Qianzhen
author_sort Dong, Yi
collection PubMed
description PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implantation in older patients have not been reported. This study aimed to evaluate the early outcomes of the TBSG technique in older patients with ATAAD. METHODS: From February 2015 to December 2020, 640 patients who simultaneously underwent an emergent open aortic surgery and TBSG implantation for ATAAD were enrolled in this study. They were categorized into the younger (age ≤ 70 years old, n = 573) and older groups (age > 70 years, n = 67). Clinical data of all patients were retrospectively reviewed. RESULT: The mean ages of the patients in the younger and older groups were 45.3 ± 9.6 years old and 73.5 ± 3.0 years old, respectively. Preoperative characteristics were similar between the two groups, except for weight and incidence of moderate or greater aortic regurgitation, which were lower in the older group than those in the younger group. Surgical procedure and duration (i.e., duration for cardiopulmonary bypass, aortic cross-clamp, selected cerebral perfusion, and total circulation arrest) were comparable between the two groups (p > 0.05). Patients in the older group had higher incidence of dialysis for acute kidney injury and longer ICU stay compared with those in the younger group. However, the incidences of 30-day mortality (5.1% in younger group vs. 7.5% in older group, p = 0.407) and other major complications (i.e., neurological adverse events) were similar between the two groups. CONCLUSION: TBSG implantation for ATAAD resulted in an acceptable mortality rate in patients above 70 years old, thus, it could be a feasible surgical procedure to perform in older patients with ATAAD when a TAR is required.
format Online
Article
Text
id pubmed-10617069
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-106170692023-11-01 Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection Dong, Yi Wang, Xuefei Chen, Liangwan Wu, Qingsong Li, Qianzhen BMC Cardiovasc Disord Research PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implantation in older patients have not been reported. This study aimed to evaluate the early outcomes of the TBSG technique in older patients with ATAAD. METHODS: From February 2015 to December 2020, 640 patients who simultaneously underwent an emergent open aortic surgery and TBSG implantation for ATAAD were enrolled in this study. They were categorized into the younger (age ≤ 70 years old, n = 573) and older groups (age > 70 years, n = 67). Clinical data of all patients were retrospectively reviewed. RESULT: The mean ages of the patients in the younger and older groups were 45.3 ± 9.6 years old and 73.5 ± 3.0 years old, respectively. Preoperative characteristics were similar between the two groups, except for weight and incidence of moderate or greater aortic regurgitation, which were lower in the older group than those in the younger group. Surgical procedure and duration (i.e., duration for cardiopulmonary bypass, aortic cross-clamp, selected cerebral perfusion, and total circulation arrest) were comparable between the two groups (p > 0.05). Patients in the older group had higher incidence of dialysis for acute kidney injury and longer ICU stay compared with those in the younger group. However, the incidences of 30-day mortality (5.1% in younger group vs. 7.5% in older group, p = 0.407) and other major complications (i.e., neurological adverse events) were similar between the two groups. CONCLUSION: TBSG implantation for ATAAD resulted in an acceptable mortality rate in patients above 70 years old, thus, it could be a feasible surgical procedure to perform in older patients with ATAAD when a TAR is required. BioMed Central 2023-10-31 /pmc/articles/PMC10617069/ /pubmed/37907843 http://dx.doi.org/10.1186/s12872-023-03513-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Dong, Yi
Wang, Xuefei
Chen, Liangwan
Wu, Qingsong
Li, Qianzhen
Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title_full Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title_fullStr Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title_full_unstemmed Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title_short Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
title_sort early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617069/
https://www.ncbi.nlm.nih.gov/pubmed/37907843
http://dx.doi.org/10.1186/s12872-023-03513-3
work_keys_str_mv AT dongyi earlyoutcomesofatriplebranchedstentgraftimplantationinelderlypatientswithacutetypeaaorticdissection
AT wangxuefei earlyoutcomesofatriplebranchedstentgraftimplantationinelderlypatientswithacutetypeaaorticdissection
AT chenliangwan earlyoutcomesofatriplebranchedstentgraftimplantationinelderlypatientswithacutetypeaaorticdissection
AT wuqingsong earlyoutcomesofatriplebranchedstentgraftimplantationinelderlypatientswithacutetypeaaorticdissection
AT liqianzhen earlyoutcomesofatriplebranchedstentgraftimplantationinelderlypatientswithacutetypeaaorticdissection