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Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection
PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implanta...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617069/ https://www.ncbi.nlm.nih.gov/pubmed/37907843 http://dx.doi.org/10.1186/s12872-023-03513-3 |
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author | Dong, Yi Wang, Xuefei Chen, Liangwan Wu, Qingsong Li, Qianzhen |
author_facet | Dong, Yi Wang, Xuefei Chen, Liangwan Wu, Qingsong Li, Qianzhen |
author_sort | Dong, Yi |
collection | PubMed |
description | PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implantation in older patients have not been reported. This study aimed to evaluate the early outcomes of the TBSG technique in older patients with ATAAD. METHODS: From February 2015 to December 2020, 640 patients who simultaneously underwent an emergent open aortic surgery and TBSG implantation for ATAAD were enrolled in this study. They were categorized into the younger (age ≤ 70 years old, n = 573) and older groups (age > 70 years, n = 67). Clinical data of all patients were retrospectively reviewed. RESULT: The mean ages of the patients in the younger and older groups were 45.3 ± 9.6 years old and 73.5 ± 3.0 years old, respectively. Preoperative characteristics were similar between the two groups, except for weight and incidence of moderate or greater aortic regurgitation, which were lower in the older group than those in the younger group. Surgical procedure and duration (i.e., duration for cardiopulmonary bypass, aortic cross-clamp, selected cerebral perfusion, and total circulation arrest) were comparable between the two groups (p > 0.05). Patients in the older group had higher incidence of dialysis for acute kidney injury and longer ICU stay compared with those in the younger group. However, the incidences of 30-day mortality (5.1% in younger group vs. 7.5% in older group, p = 0.407) and other major complications (i.e., neurological adverse events) were similar between the two groups. CONCLUSION: TBSG implantation for ATAAD resulted in an acceptable mortality rate in patients above 70 years old, thus, it could be a feasible surgical procedure to perform in older patients with ATAAD when a TAR is required. |
format | Online Article Text |
id | pubmed-10617069 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-106170692023-11-01 Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection Dong, Yi Wang, Xuefei Chen, Liangwan Wu, Qingsong Li, Qianzhen BMC Cardiovasc Disord Research PURPOSE: Older patients with acute type A aortic dissection (ATAAD) have higher risk of mortality than that of younger patients when a total arch reconstruction (TAR) is required. Triple-branched stent graft (TBSG) implantation is a novel technique for TAR. However, early outcomes of a TBSG implantation in older patients have not been reported. This study aimed to evaluate the early outcomes of the TBSG technique in older patients with ATAAD. METHODS: From February 2015 to December 2020, 640 patients who simultaneously underwent an emergent open aortic surgery and TBSG implantation for ATAAD were enrolled in this study. They were categorized into the younger (age ≤ 70 years old, n = 573) and older groups (age > 70 years, n = 67). Clinical data of all patients were retrospectively reviewed. RESULT: The mean ages of the patients in the younger and older groups were 45.3 ± 9.6 years old and 73.5 ± 3.0 years old, respectively. Preoperative characteristics were similar between the two groups, except for weight and incidence of moderate or greater aortic regurgitation, which were lower in the older group than those in the younger group. Surgical procedure and duration (i.e., duration for cardiopulmonary bypass, aortic cross-clamp, selected cerebral perfusion, and total circulation arrest) were comparable between the two groups (p > 0.05). Patients in the older group had higher incidence of dialysis for acute kidney injury and longer ICU stay compared with those in the younger group. However, the incidences of 30-day mortality (5.1% in younger group vs. 7.5% in older group, p = 0.407) and other major complications (i.e., neurological adverse events) were similar between the two groups. CONCLUSION: TBSG implantation for ATAAD resulted in an acceptable mortality rate in patients above 70 years old, thus, it could be a feasible surgical procedure to perform in older patients with ATAAD when a TAR is required. BioMed Central 2023-10-31 /pmc/articles/PMC10617069/ /pubmed/37907843 http://dx.doi.org/10.1186/s12872-023-03513-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Dong, Yi Wang, Xuefei Chen, Liangwan Wu, Qingsong Li, Qianzhen Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title | Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title_full | Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title_fullStr | Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title_full_unstemmed | Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title_short | Early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
title_sort | early outcomes of a triple-branched stent graft implantation in elderly patients with acute type a aortic dissection |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617069/ https://www.ncbi.nlm.nih.gov/pubmed/37907843 http://dx.doi.org/10.1186/s12872-023-03513-3 |
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