New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023

We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify...

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Autores principales: Mwanga, Mike J., Lambisia, Arnold W., Morobe, John Mwita, Murunga, Nickson, Moraa, Edidah, Ndwiga, Leonard, Cheruiyot, Robinson, Musyoki, Jennifer, Mutunga, Martin, Guzman-Rincon, Laura M., Sande, Charles, Mwangangi, Joseph, Bejon, Philip, Ochola-Oyier, Lynette Isabella, Nokes, D. James, Agoti, Charles N., Nyiro, Joyce, Githinji, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617346/
https://www.ncbi.nlm.nih.gov/pubmed/37708843
http://dx.doi.org/10.3201/eid2911.230894
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author Mwanga, Mike J.
Lambisia, Arnold W.
Morobe, John Mwita
Murunga, Nickson
Moraa, Edidah
Ndwiga, Leonard
Cheruiyot, Robinson
Musyoki, Jennifer
Mutunga, Martin
Guzman-Rincon, Laura M.
Sande, Charles
Mwangangi, Joseph
Bejon, Philip
Ochola-Oyier, Lynette Isabella
Nokes, D. James
Agoti, Charles N.
Nyiro, Joyce
Githinji, George
author_facet Mwanga, Mike J.
Lambisia, Arnold W.
Morobe, John Mwita
Murunga, Nickson
Moraa, Edidah
Ndwiga, Leonard
Cheruiyot, Robinson
Musyoki, Jennifer
Mutunga, Martin
Guzman-Rincon, Laura M.
Sande, Charles
Mwangangi, Joseph
Bejon, Philip
Ochola-Oyier, Lynette Isabella
Nokes, D. James
Agoti, Charles N.
Nyiro, Joyce
Githinji, George
author_sort Mwanga, Mike J.
collection PubMed
description We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify new lineages to inform COVID-19 outbreak prevention.
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spelling pubmed-106173462023-11-01 New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023 Mwanga, Mike J. Lambisia, Arnold W. Morobe, John Mwita Murunga, Nickson Moraa, Edidah Ndwiga, Leonard Cheruiyot, Robinson Musyoki, Jennifer Mutunga, Martin Guzman-Rincon, Laura M. Sande, Charles Mwangangi, Joseph Bejon, Philip Ochola-Oyier, Lynette Isabella Nokes, D. James Agoti, Charles N. Nyiro, Joyce Githinji, George Emerg Infect Dis Research Letter We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify new lineages to inform COVID-19 outbreak prevention. Centers for Disease Control and Prevention 2023-11 /pmc/articles/PMC10617346/ /pubmed/37708843 http://dx.doi.org/10.3201/eid2911.230894 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Mwanga, Mike J.
Lambisia, Arnold W.
Morobe, John Mwita
Murunga, Nickson
Moraa, Edidah
Ndwiga, Leonard
Cheruiyot, Robinson
Musyoki, Jennifer
Mutunga, Martin
Guzman-Rincon, Laura M.
Sande, Charles
Mwangangi, Joseph
Bejon, Philip
Ochola-Oyier, Lynette Isabella
Nokes, D. James
Agoti, Charles N.
Nyiro, Joyce
Githinji, George
New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title_full New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title_fullStr New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title_full_unstemmed New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title_short New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023
title_sort new sars-cov-2 omicron variant with spike protein mutation y451h, kilifi, kenya, march–may 2023
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617346/
https://www.ncbi.nlm.nih.gov/pubmed/37708843
http://dx.doi.org/10.3201/eid2911.230894
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