Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer

With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being...

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Autores principales: Hartkopf, Andreas D., Fehm, Tanja N., Welslau, Manfred, Müller, Volkmar, Schütz, Florian, Fasching, Peter A., Janni, Wolfgang, Witzel, Isabell, Thomssen, Christoph, Beierlein, Milena, Belleville, Erik, Untch, Michael, Thill, Marc, Tesch, Hans, Ditsch, Nina, Lux, Michael P., Aktas, Bahriye, Banys-Paluchowski, Maggie, Kolberg-Liedtke, Cornelia, Wöckel, Achim, Kolberg, Hans-Christian, Harbeck, Nadia, Stickeler, Elmar, Bartsch, Rupert, Schneeweiss, Andreas, Ettl, Johannes, Würstlein, Rachel, Krug, David, Taran, Florin-Andrei, Lüftner, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617391/
https://www.ncbi.nlm.nih.gov/pubmed/37916183
http://dx.doi.org/10.1055/a-2074-0551
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author Hartkopf, Andreas D.
Fehm, Tanja N.
Welslau, Manfred
Müller, Volkmar
Schütz, Florian
Fasching, Peter A.
Janni, Wolfgang
Witzel, Isabell
Thomssen, Christoph
Beierlein, Milena
Belleville, Erik
Untch, Michael
Thill, Marc
Tesch, Hans
Ditsch, Nina
Lux, Michael P.
Aktas, Bahriye
Banys-Paluchowski, Maggie
Kolberg-Liedtke, Cornelia
Wöckel, Achim
Kolberg, Hans-Christian
Harbeck, Nadia
Stickeler, Elmar
Bartsch, Rupert
Schneeweiss, Andreas
Ettl, Johannes
Würstlein, Rachel
Krug, David
Taran, Florin-Andrei
Lüftner, Diana
author_facet Hartkopf, Andreas D.
Fehm, Tanja N.
Welslau, Manfred
Müller, Volkmar
Schütz, Florian
Fasching, Peter A.
Janni, Wolfgang
Witzel, Isabell
Thomssen, Christoph
Beierlein, Milena
Belleville, Erik
Untch, Michael
Thill, Marc
Tesch, Hans
Ditsch, Nina
Lux, Michael P.
Aktas, Bahriye
Banys-Paluchowski, Maggie
Kolberg-Liedtke, Cornelia
Wöckel, Achim
Kolberg, Hans-Christian
Harbeck, Nadia
Stickeler, Elmar
Bartsch, Rupert
Schneeweiss, Andreas
Ettl, Johannes
Würstlein, Rachel
Krug, David
Taran, Florin-Andrei
Lüftner, Diana
author_sort Hartkopf, Andreas D.
collection PubMed
description With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months.
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spelling pubmed-106173912023-11-01 Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer Hartkopf, Andreas D. Fehm, Tanja N. Welslau, Manfred Müller, Volkmar Schütz, Florian Fasching, Peter A. Janni, Wolfgang Witzel, Isabell Thomssen, Christoph Beierlein, Milena Belleville, Erik Untch, Michael Thill, Marc Tesch, Hans Ditsch, Nina Lux, Michael P. Aktas, Bahriye Banys-Paluchowski, Maggie Kolberg-Liedtke, Cornelia Wöckel, Achim Kolberg, Hans-Christian Harbeck, Nadia Stickeler, Elmar Bartsch, Rupert Schneeweiss, Andreas Ettl, Johannes Würstlein, Rachel Krug, David Taran, Florin-Andrei Lüftner, Diana Geburtshilfe Frauenheilkd With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months. Georg Thieme Verlag KG 2023-06-06 /pmc/articles/PMC10617391/ /pubmed/37916183 http://dx.doi.org/10.1055/a-2074-0551 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Hartkopf, Andreas D.
Fehm, Tanja N.
Welslau, Manfred
Müller, Volkmar
Schütz, Florian
Fasching, Peter A.
Janni, Wolfgang
Witzel, Isabell
Thomssen, Christoph
Beierlein, Milena
Belleville, Erik
Untch, Michael
Thill, Marc
Tesch, Hans
Ditsch, Nina
Lux, Michael P.
Aktas, Bahriye
Banys-Paluchowski, Maggie
Kolberg-Liedtke, Cornelia
Wöckel, Achim
Kolberg, Hans-Christian
Harbeck, Nadia
Stickeler, Elmar
Bartsch, Rupert
Schneeweiss, Andreas
Ettl, Johannes
Würstlein, Rachel
Krug, David
Taran, Florin-Andrei
Lüftner, Diana
Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title_full Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title_fullStr Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title_full_unstemmed Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title_short Update Breast Cancer 2023 Part 1 – Early Stage Breast Cancer
title_sort update breast cancer 2023 part 1 – early stage breast cancer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617391/
https://www.ncbi.nlm.nih.gov/pubmed/37916183
http://dx.doi.org/10.1055/a-2074-0551
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