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Ubiquitin E3 ligase SPOP is a host negative regulator of enterovirus 71-encoded 2A protease

The 2A protease (2A(pro)) encoded by enterovirus 71 (EV71) serves as an accessory protein with significant involvement in the regulation of EV71 infection and viral replication. EV71-2A(pro) exhibits the ability to suppress various host factors, thereby disrupting the cellular antiviral immune respo...

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Detalles Bibliográficos
Autores principales: Zang, Lichao, Yang, Xinyu, Chen, Yan, Huang, Fan, Yuan, Yukang, Chen, Xiangjie, Zuo, Yibo, Miao, Ying, Gu, Jin, Guo, Hui, Xia, Wenxin, Peng, Yang, Tang, Mengyuan, Huang, Ziwei, Wang, Yangyang, Ma, Jinhong, Jiang, Jingting, Zhou, Wei, Zheng, Hui, Shi, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617436/
https://www.ncbi.nlm.nih.gov/pubmed/37796126
http://dx.doi.org/10.1128/jvi.00786-23