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Isolation of novel simian adenoviruses from macaques for development of a vector for human gene therapy and vaccines
Both human and non-human simian adenoviruses (HAdVs and SAdVs, respectively) have been used as gene therapy and vaccine vectors. The high prevalence of HAdVs and the neutralizing antibodies associated with prior infection, may limit HAdV-based vector use in human subjects. To overcome this drawback,...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617444/ https://www.ncbi.nlm.nih.gov/pubmed/37712705 http://dx.doi.org/10.1128/jvi.01014-23 |