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HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34(+) hematopoietic progenitor cells

Human cytomegalovirus (HCMV) is a species-specific virus that establishes a persistent/latent infection in CD34(+) hematopoietic progenitor cells (HPCs). The ability of HCMV to reactivate from latency is exquisitely linked to changes in cell signaling, which result in HPC differentiation. The Wnt/β-...

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Detalles Bibliográficos
Autores principales: Dirck, Aaron, Diggins, Nicole L., Crawford, Lindsey B., Perez, Wilma D., Parkins, Christopher J., Struthers, Hillary H., Turner, Rebekah, Pham, Andrew H., Mitchell, Jennifer, Papen, Courtney R., Malouli, Daniel, Hancock, Meaghan H., Caposio, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617580/
https://www.ncbi.nlm.nih.gov/pubmed/37772824
http://dx.doi.org/10.1128/jvi.01241-23

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