Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure

Consumption of low dietary potassium, common with ultraprocessed foods, activates the thiazide-sensitive sodium chloride cotransporter (NCC) via the with no (K) lysine kinase/STE20/SPS1-related proline-alanine–rich protein kinase (WNK/SPAK) pathway to induce salt retention and elevate blood pressure...

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Detalles Bibliográficos
Autores principales: Grimm, P. Richard, Tatomir, Anamaria, Rosenbaek, Lena L., Kim, Bo Young, Li, Dimin, Delpire, Eric J., Fenton, Robert A., Welling, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617769/
https://www.ncbi.nlm.nih.gov/pubmed/37676724
http://dx.doi.org/10.1172/JCI158498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617769/
https://www.ncbi.nlm.nih.gov/pubmed/37676724
http://dx.doi.org/10.1172/JCI158498

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