Proviral location affects cognate peptide–induced virus production and immune recognition of HIV-1–infected T cell clones

BACKGROUND: HIV-1–infected CD4(+) T cells contribute to latent reservoir persistence by proliferating while avoiding immune recognition. Integration features of intact proviruses in elite controllers (ECs) and people on long-term therapy suggest that proviruses in specific chromosomal locations can...

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Detalles Bibliográficos
Autores principales: Dragoni, Filippo, Kwaa, Abena K., Traut, Caroline C., Veenhuis, Rebecca T., Woldemeskel, Bezawit A., Camilo-Contreras, Angelica, Raymond, Hayley E., Dykema, Arbor G., Scully, Eileen P., Rosecrans, Amanda M., Smith, Kellie N., Bushman, Frederic D., Simonetti, Francesco R., Blankson, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617777/
https://www.ncbi.nlm.nih.gov/pubmed/37698927
http://dx.doi.org/10.1172/JCI171097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617777/
https://www.ncbi.nlm.nih.gov/pubmed/37698927
http://dx.doi.org/10.1172/JCI171097

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