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Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis

AIMS: Currently, the effect of drug treatment for osteoporosis is relatively poor, and the side effects are numerous and serious. Melatonin is a potential drug to improve bone mass in postmenopausal women. Unfortunately, the mechanism by which melatonin improves bone metabolism remains unclear. The...

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Detalles Bibliográficos
Autores principales: Wang, Xiaochuan, Jiang, Wen, Pan, Kexin, Tao, Lin, Zhu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618049/
https://www.ncbi.nlm.nih.gov/pubmed/37907083
http://dx.doi.org/10.1302/2046-3758.1211.BJR-2022-0425.R3