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Tumor suppressor Parkin induces p53-mediated cell cycle arrest in human lung and colorectal cancer cells

Dysregulation of the E3 ubiquitin ligase Parkin has been linked to various human cancers, indicating that Parkin is a tumor suppressor protein. However, the mechanisms of action of Parkin remain unclear to date. Thus, we aimed to elucidate the mechanisms of action of Parkin as a tumor suppressor in...

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Detalles Bibliográficos
Autores principales: Jung, Byung Chul, Kim, Sung Hoon, Cho, Yoonjung, Kim, Yoon Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618076/
https://www.ncbi.nlm.nih.gov/pubmed/37679297
http://dx.doi.org/10.5483/BMBRep.2023-0134