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author Uhlhaas, Peter J.
Davey, Christopher G.
Mehta, Urvakhsh Meherwan
Shah, Jai
Torous, John
Allen, Nicholas B.
Avenevoli, Shelli
Bella-Awusah, Tolulope
Chanen, Andrew
Chen, Eric Y. H.
Correll, Christoph U.
Do, Kim Q.
Fisher, Helen L.
Frangou, Sophia
Hickie, Ian B.
Keshavan, Matcheri S.
Konrad, Kerstin
Lee, Francis S.
Liu, Cindy H.
Luna, Beatriz
McGorry, Patrick D.
Meyer-Lindenberg, Andreas
Nordentoft, Merete
Öngür, Dost
Patton, George C.
Paus, Tomáš
Reininghaus, Ulrich
Sawa, Akira
Schoenbaum, Michael
Schumann, Gunter
Srihari, Vinod H.
Susser, Ezra
Verma, Swapna K.
Woo, T. Wilson
Yang, Lawrence H.
Yung, Alison R.
Wood, Stephen J.
author_facet Uhlhaas, Peter J.
Davey, Christopher G.
Mehta, Urvakhsh Meherwan
Shah, Jai
Torous, John
Allen, Nicholas B.
Avenevoli, Shelli
Bella-Awusah, Tolulope
Chanen, Andrew
Chen, Eric Y. H.
Correll, Christoph U.
Do, Kim Q.
Fisher, Helen L.
Frangou, Sophia
Hickie, Ian B.
Keshavan, Matcheri S.
Konrad, Kerstin
Lee, Francis S.
Liu, Cindy H.
Luna, Beatriz
McGorry, Patrick D.
Meyer-Lindenberg, Andreas
Nordentoft, Merete
Öngür, Dost
Patton, George C.
Paus, Tomáš
Reininghaus, Ulrich
Sawa, Akira
Schoenbaum, Michael
Schumann, Gunter
Srihari, Vinod H.
Susser, Ezra
Verma, Swapna K.
Woo, T. Wilson
Yang, Lawrence H.
Yung, Alison R.
Wood, Stephen J.
author_sort Uhlhaas, Peter J.
collection PubMed
description Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
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spelling pubmed-106181052023-11-02 Towards a youth mental health paradigm: a perspective and roadmap Uhlhaas, Peter J. Davey, Christopher G. Mehta, Urvakhsh Meherwan Shah, Jai Torous, John Allen, Nicholas B. Avenevoli, Shelli Bella-Awusah, Tolulope Chanen, Andrew Chen, Eric Y. H. Correll, Christoph U. Do, Kim Q. Fisher, Helen L. Frangou, Sophia Hickie, Ian B. Keshavan, Matcheri S. Konrad, Kerstin Lee, Francis S. Liu, Cindy H. Luna, Beatriz McGorry, Patrick D. Meyer-Lindenberg, Andreas Nordentoft, Merete Öngür, Dost Patton, George C. Paus, Tomáš Reininghaus, Ulrich Sawa, Akira Schoenbaum, Michael Schumann, Gunter Srihari, Vinod H. Susser, Ezra Verma, Swapna K. Woo, T. Wilson Yang, Lawrence H. Yung, Alison R. Wood, Stephen J. Mol Psychiatry Perspective Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders. Nature Publishing Group UK 2023-08-14 2023 /pmc/articles/PMC10618105/ /pubmed/37580524 http://dx.doi.org/10.1038/s41380-023-02202-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Perspective
Uhlhaas, Peter J.
Davey, Christopher G.
Mehta, Urvakhsh Meherwan
Shah, Jai
Torous, John
Allen, Nicholas B.
Avenevoli, Shelli
Bella-Awusah, Tolulope
Chanen, Andrew
Chen, Eric Y. H.
Correll, Christoph U.
Do, Kim Q.
Fisher, Helen L.
Frangou, Sophia
Hickie, Ian B.
Keshavan, Matcheri S.
Konrad, Kerstin
Lee, Francis S.
Liu, Cindy H.
Luna, Beatriz
McGorry, Patrick D.
Meyer-Lindenberg, Andreas
Nordentoft, Merete
Öngür, Dost
Patton, George C.
Paus, Tomáš
Reininghaus, Ulrich
Sawa, Akira
Schoenbaum, Michael
Schumann, Gunter
Srihari, Vinod H.
Susser, Ezra
Verma, Swapna K.
Woo, T. Wilson
Yang, Lawrence H.
Yung, Alison R.
Wood, Stephen J.
Towards a youth mental health paradigm: a perspective and roadmap
title Towards a youth mental health paradigm: a perspective and roadmap
title_full Towards a youth mental health paradigm: a perspective and roadmap
title_fullStr Towards a youth mental health paradigm: a perspective and roadmap
title_full_unstemmed Towards a youth mental health paradigm: a perspective and roadmap
title_short Towards a youth mental health paradigm: a perspective and roadmap
title_sort towards a youth mental health paradigm: a perspective and roadmap
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618105/
https://www.ncbi.nlm.nih.gov/pubmed/37580524
http://dx.doi.org/10.1038/s41380-023-02202-z
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