Cargando…
Diet-induced rewiring of the Wnt gene regulatory network connects aberrant splicing to fatty liver and liver cancer in DIAMOND mice
Several preclinical models have been recently developed for metabolic associated fatty liver disease (MAFLD) and associated hepatocellular carcinoma (HCC) but comprehensive analysis of the regulatory and transcriptional landscapes underlying disease in these models are still missing. We investigated...
Autores principales: | López-Pérez, Ana, Remeseiro, Silvia, Hörnblad, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618177/ https://www.ncbi.nlm.nih.gov/pubmed/37907668 http://dx.doi.org/10.1038/s41598-023-45614-1 |
Ejemplares similares
-
Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication
por: Chakraborty, Chaitali, et al.
Publicado: (2023) -
Epigenetics, Enhancer Function and 3D Chromatin Organization in Reprogramming to Pluripotency
por: Hörnblad, Andreas, et al.
Publicado: (2022) -
Pan-AMPK activator O304 prevents gene expression changes and remobilisation of histone marks in islets of diet-induced obese mice
por: López-Pérez, Ana, et al.
Publicado: (2021) -
Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide
por: Vincent, Craig A., et al.
Publicado: (2023) -
Alternative Splicing Rewires Hippo Signaling Pathway in Hepatocytes to Promote Liver Regeneration
por: Bangru, Sushant, et al.
Publicado: (2018)