Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease

Castleman disease (CD) is a rare lymphoproliferative disorder. Among subtypes of CD, idiopathic multicentric CD-not otherwise specified (iMCD-NOS) has a poor prognosis and its pathogenesis is largely unknown. Here we present a xenotransplantation model of iMCD-NOS pathogenesis. Immunodeficient mice,...

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Detalles Bibliográficos
Autores principales: Harada, Takuya, Kikushige, Yoshikane, Miyamoto, Toshihiro, Uno, Kazuko, Niiro, Hiroaki, Kawakami, Atsushi, Koga, Tomohiro, Akashi, Koichi, Yoshizaki, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618253/
https://www.ncbi.nlm.nih.gov/pubmed/37907518
http://dx.doi.org/10.1038/s41467-023-42718-0

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