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Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex
O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal signals, O-GlcNAcylation regulates diverse cellular processes by modulating the stability, structure, and function of target...
Autores principales: | Lu, Ping, Liu, Yusong, He, Maozhou, Cao, Ting, Yang, Mengquan, Qi, Shutao, Yu, Hongtao, Gao, Haishan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618255/ https://www.ncbi.nlm.nih.gov/pubmed/37907462 http://dx.doi.org/10.1038/s41467-023-42427-8 |
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