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Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population
PURPOSE: Antidepressant use has increased in many European countries, mostly driven by longer treatment duration. The aim of this study was to provide prevalence rates of long-term users of antidepressants for the Swiss population over the last decade and to investigate associated factors for longer...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618304/ https://www.ncbi.nlm.nih.gov/pubmed/37668659 http://dx.doi.org/10.1007/s00228-023-03559-4 |
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author | Amrein, Melanie A. Hengartner, Michael P. Näpflin, Markus Farcher, Renato Huber, Carola A. |
author_facet | Amrein, Melanie A. Hengartner, Michael P. Näpflin, Markus Farcher, Renato Huber, Carola A. |
author_sort | Amrein, Melanie A. |
collection | PubMed |
description | PURPOSE: Antidepressant use has increased in many European countries, mostly driven by longer treatment duration. The aim of this study was to provide prevalence rates of long-term users of antidepressants for the Swiss population over the last decade and to investigate associated factors for longer use. METHODS: We examined the prevalence rates of individuals with at least one prescription for antidepressants using longitudinal health claims data for 2013 to 2021. We defined short- (< one year), medium- (one–two years), and long-term users (> two years) for 2015 to 2019. We applied a binary logistic regression model to investigate the effects of population (gender, age, area of living, language, health insurance plan, and nursing home) and treatment characteristics (psychiatric or psychotherapeutic care) on long-term compared to short- and medium-term users in 2019. RESULTS: In 2021, 9% of the Swiss population (n = 770,698) received at least one antidepressant prescription, which remained stable since 2013. In 2019, the proportion of long-term users was 57.4%, with steady increase since 2015. The proportion of medium- and short-term users has decreased. Older age, being a woman, living in an urban area, living in a nursing home, being enrolled in a standard care plan, and receiving psychiatric or psychotherapeutic care were factors positively associated with being a long-term user. CONCLUSION: The proportion of long-term users in Switzerland is high and steadily increasing. Given the ongoing debate about the confounding effects of relapse and withdrawal, more research is needed to investigate longer use of antidepressants that could indicate overprescribing. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00228-023-03559-4. |
format | Online Article Text |
id | pubmed-10618304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-106183042023-11-02 Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population Amrein, Melanie A. Hengartner, Michael P. Näpflin, Markus Farcher, Renato Huber, Carola A. Eur J Clin Pharmacol Research PURPOSE: Antidepressant use has increased in many European countries, mostly driven by longer treatment duration. The aim of this study was to provide prevalence rates of long-term users of antidepressants for the Swiss population over the last decade and to investigate associated factors for longer use. METHODS: We examined the prevalence rates of individuals with at least one prescription for antidepressants using longitudinal health claims data for 2013 to 2021. We defined short- (< one year), medium- (one–two years), and long-term users (> two years) for 2015 to 2019. We applied a binary logistic regression model to investigate the effects of population (gender, age, area of living, language, health insurance plan, and nursing home) and treatment characteristics (psychiatric or psychotherapeutic care) on long-term compared to short- and medium-term users in 2019. RESULTS: In 2021, 9% of the Swiss population (n = 770,698) received at least one antidepressant prescription, which remained stable since 2013. In 2019, the proportion of long-term users was 57.4%, with steady increase since 2015. The proportion of medium- and short-term users has decreased. Older age, being a woman, living in an urban area, living in a nursing home, being enrolled in a standard care plan, and receiving psychiatric or psychotherapeutic care were factors positively associated with being a long-term user. CONCLUSION: The proportion of long-term users in Switzerland is high and steadily increasing. Given the ongoing debate about the confounding effects of relapse and withdrawal, more research is needed to investigate longer use of antidepressants that could indicate overprescribing. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00228-023-03559-4. Springer Berlin Heidelberg 2023-09-05 2023 /pmc/articles/PMC10618304/ /pubmed/37668659 http://dx.doi.org/10.1007/s00228-023-03559-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Amrein, Melanie A. Hengartner, Michael P. Näpflin, Markus Farcher, Renato Huber, Carola A. Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title | Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title_full | Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title_fullStr | Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title_full_unstemmed | Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title_short | Prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult Swiss general population |
title_sort | prevalence, trends, and individual patterns of long-term antidepressant medication use in the adult swiss general population |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618304/ https://www.ncbi.nlm.nih.gov/pubmed/37668659 http://dx.doi.org/10.1007/s00228-023-03559-4 |
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