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Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design
Pteridine reductase 1 (PTR1) is a folate and pterin pathway enzyme unique for pathogenic trypanosomatids. As a validated drug target, PTR1 has been the focus of recent research efforts aimed at finding more effective treatments against human parasitic diseases such as leishmaniasis or sleeping sickn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618315/ https://www.ncbi.nlm.nih.gov/pubmed/37608196 http://dx.doi.org/10.1007/s00249-023-01677-6 |