SYVN1 ubiquitinates FoxO1 to induce β-catenin nuclear translocation, PD-L1-mediated metastasis, and immune evasion of hepatocellular carcinoma

BACKGROUND: A high incidence of hepatocellular carcinoma (HCC), the most frequently diagnosed form of liver cancer, is observed in Africa and Asia. SYVN1 is upregulated in HCC; however, the biological roles of SYVN1 in immune evasion remain unclear. METHODS: RT-qPCR and western blot were employed to...

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Detalles Bibliográficos
Autores principales: Xie, Wei, Shi, Lei, Quan, Hu, Xiao, Hua, Chen, Jie, Liu, Jia, de Dieu Habimana, Jean, Huang, Rongqi, Luo, Jia, Chen, Pan, Li, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618324/
https://www.ncbi.nlm.nih.gov/pubmed/37099251
http://dx.doi.org/10.1007/s13402-023-00811-y

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