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Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (–)-epicatechin

MurC, D, E, and F are ATP-dependent ligases involved in the stepwise assembly of the tetrapeptide stem of forming peptidoglycan. As highly conserved targets found exclusively in bacterial cells, they are of significant interest for antibacterial drug discovery. In this study, we employed a computer-...

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Detalles Bibliográficos
Autores principales: Rambaher, Martina Hrast, Zdovc, Irena, Glavač, Nina Kočevar, Gobec, Stanislav, Frlan, Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618370/
https://www.ncbi.nlm.nih.gov/pubmed/37796382
http://dx.doi.org/10.1007/s10822-023-00535-z

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