Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells

Glioblastoma is thought to originate from neural stem cells (NSCs) of the subventricular zone that acquire genetic alterations. In the adult brain, NSCs are largely quiescent, suggesting that deregulation of quiescence maintenance may be a prerequisite for tumor initiation. Although inactivation of...

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Detalles Bibliográficos
Autores principales: Amodeo, Valeria, Davies, Timothy, Martinez-Segura, Amalia, Clements, Melanie P., Ragdale, Holly Simpson, Bailey, Andrew, Dos Santos, Mariana Silva, MacRae, James I., Mokochinski, Joao, Kramer, Holger, Garcia-Diaz, Claudia, Gould, Alex P., Marguerat, Samuel, Parrinello, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618406/
https://www.ncbi.nlm.nih.gov/pubmed/37084728
http://dx.doi.org/10.1016/j.devcel.2023.03.021

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