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The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos

The single cell layer of surface ectoderm (SE) which overlies the closing neural tube (NT) plays a crucial biomechanical role during mammalian NT closure (NTC), challenging previous assumptions that it is only passive to the force-generating neuroepithelium (NE). Failure of NTC leads to congenital m...

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Detalles Bibliográficos
Autores principales: Marshall, Abigail R., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618430/
https://www.ncbi.nlm.nih.gov/pubmed/37068590
http://dx.doi.org/10.1016/j.cdev.2023.203840

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