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The surface ectoderm exhibits spatially heterogenous tension that correlates with YAP localisation during spinal neural tube closure in mouse embryos
The single cell layer of surface ectoderm (SE) which overlies the closing neural tube (NT) plays a crucial biomechanical role during mammalian NT closure (NTC), challenging previous assumptions that it is only passive to the force-generating neuroepithelium (NE). Failure of NTC leads to congenital m...
Autores principales: | Marshall, Abigail R., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618430/ https://www.ncbi.nlm.nih.gov/pubmed/37068590 http://dx.doi.org/10.1016/j.cdev.2023.203840 |
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