Cargando…
Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study
BACKGROUND AND AIMS: The study aimed to collect and compare clinical and laboratory findings of children with severe and nonsevere COVID‐19 in Kermanshah City, located in the west of Iran. METHODS: The study was conducted on 500 children with COVID‐19 hospitalized in Mohammad‐Kermanshahi Hospital in...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618436/ https://www.ncbi.nlm.nih.gov/pubmed/37920662 http://dx.doi.org/10.1002/hsr2.1659 |
_version_ | 1785129775070707712 |
---|---|
author | Nemati Zargaran, Fatemeh Rostamian, Mosayeb Alimoradi, Saeed Rezaeian, Shahab Javadirad, Etrat Chegene Lorestani, Roya Motamed, Hajar Hasanpourshahlaei, Mahtab Rostami, Elham Ghadiri, Keyghobad |
author_facet | Nemati Zargaran, Fatemeh Rostamian, Mosayeb Alimoradi, Saeed Rezaeian, Shahab Javadirad, Etrat Chegene Lorestani, Roya Motamed, Hajar Hasanpourshahlaei, Mahtab Rostami, Elham Ghadiri, Keyghobad |
author_sort | Nemati Zargaran, Fatemeh |
collection | PubMed |
description | BACKGROUND AND AIMS: The study aimed to collect and compare clinical and laboratory findings of children with severe and nonsevere COVID‐19 in Kermanshah City, located in the west of Iran. METHODS: The study was conducted on 500 children with COVID‐19 hospitalized in Mohammad‐Kermanshahi Hospital in Kermanshah City. Pediatric COVID‐19 was confirmed by reverse transcription‐polymerase chain reaction (RT‐PCR) test using respiratory secretion samples. Medical records were reviewed and information related to demographic characteristics, underlying diseases, clinical manifestations, laboratory findings, and chest computed tomography (CT) scans were all extracted from electronic and paper records. Patients were divided into three groups according to the severity of the disease: mild, moderate, and severe. Clinical and laboratory findings were compared between the groups and the collected data were analyzed by statistical methods. RESULTS: Out of 500 patients, 286 were boys and 214 were girls. Of the patients, 321 cases were only COVID‐19, while 179 patients were diagnosed as Multisystem Inflammatory Syndrome in Children (MIS‐C) positive. The average age of COVID‐19 patients was 3.85 ± 4.48 and of MIS‐C patients was 3.1 ± 3.5. In order, fever, cough, and heart disorders were the most common symptoms in patients with COVID‐19 and MIS‐C, respectively. In terms of disease severity, 246 patients had mild disease, 19 patients had moderate disease, and 56 patients had severe disease. In severe patients, the average number of white blood cells (WBC) was higher, while the average number of lymphocytes was lower. Also, in these patients, the average age was lower, and most of them had respiratory distress. In mild patients, often cough, diarrhea, and vomiting were observed. CONCLUSION: The results of our study showed that laboratory factors such as WBC count, lymphocyte count, CT findings, Respiratory distress, cough, diarrhea, and vomiting can be used to evaluate the severity of COVID‐19 in children. |
format | Online Article Text |
id | pubmed-10618436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106184362023-11-02 Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study Nemati Zargaran, Fatemeh Rostamian, Mosayeb Alimoradi, Saeed Rezaeian, Shahab Javadirad, Etrat Chegene Lorestani, Roya Motamed, Hajar Hasanpourshahlaei, Mahtab Rostami, Elham Ghadiri, Keyghobad Health Sci Rep Original Research BACKGROUND AND AIMS: The study aimed to collect and compare clinical and laboratory findings of children with severe and nonsevere COVID‐19 in Kermanshah City, located in the west of Iran. METHODS: The study was conducted on 500 children with COVID‐19 hospitalized in Mohammad‐Kermanshahi Hospital in Kermanshah City. Pediatric COVID‐19 was confirmed by reverse transcription‐polymerase chain reaction (RT‐PCR) test using respiratory secretion samples. Medical records were reviewed and information related to demographic characteristics, underlying diseases, clinical manifestations, laboratory findings, and chest computed tomography (CT) scans were all extracted from electronic and paper records. Patients were divided into three groups according to the severity of the disease: mild, moderate, and severe. Clinical and laboratory findings were compared between the groups and the collected data were analyzed by statistical methods. RESULTS: Out of 500 patients, 286 were boys and 214 were girls. Of the patients, 321 cases were only COVID‐19, while 179 patients were diagnosed as Multisystem Inflammatory Syndrome in Children (MIS‐C) positive. The average age of COVID‐19 patients was 3.85 ± 4.48 and of MIS‐C patients was 3.1 ± 3.5. In order, fever, cough, and heart disorders were the most common symptoms in patients with COVID‐19 and MIS‐C, respectively. In terms of disease severity, 246 patients had mild disease, 19 patients had moderate disease, and 56 patients had severe disease. In severe patients, the average number of white blood cells (WBC) was higher, while the average number of lymphocytes was lower. Also, in these patients, the average age was lower, and most of them had respiratory distress. In mild patients, often cough, diarrhea, and vomiting were observed. CONCLUSION: The results of our study showed that laboratory factors such as WBC count, lymphocyte count, CT findings, Respiratory distress, cough, diarrhea, and vomiting can be used to evaluate the severity of COVID‐19 in children. John Wiley and Sons Inc. 2023-10-31 /pmc/articles/PMC10618436/ /pubmed/37920662 http://dx.doi.org/10.1002/hsr2.1659 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Nemati Zargaran, Fatemeh Rostamian, Mosayeb Alimoradi, Saeed Rezaeian, Shahab Javadirad, Etrat Chegene Lorestani, Roya Motamed, Hajar Hasanpourshahlaei, Mahtab Rostami, Elham Ghadiri, Keyghobad Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title | Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title_full | Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title_fullStr | Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title_full_unstemmed | Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title_short | Clinical and laboratory characteristics of children with severe and nonsevere COVID‐19 in Kermanshah, west of Iran: A retrospective study |
title_sort | clinical and laboratory characteristics of children with severe and nonsevere covid‐19 in kermanshah, west of iran: a retrospective study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618436/ https://www.ncbi.nlm.nih.gov/pubmed/37920662 http://dx.doi.org/10.1002/hsr2.1659 |
work_keys_str_mv | AT nematizargaranfatemeh clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT rostamianmosayeb clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT alimoradisaeed clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT rezaeianshahab clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT javadiradetrat clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT chegenelorestaniroya clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT motamedhajar clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT hasanpourshahlaeimahtab clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT rostamielham clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy AT ghadirikeyghobad clinicalandlaboratorycharacteristicsofchildrenwithsevereandnonseverecovid19inkermanshahwestofiranaretrospectivestudy |