Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction

During tumor progression, cancer-associated fibroblasts (CAFs) accumulate in tumors and produce an excessive extracellular matrix (ECM), forming a capsule that enwraps cancer cells. This capsule acts as a barrier that restricts tumor growth leading to the buildup of intratumoral pressure. Combining...

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Detalles Bibliográficos
Autores principales: Barbazan, Jorge, Pérez-González, Carlos, Gómez-González, Manuel, Dedenon, Mathieu, Richon, Sophie, Latorre, Ernest, Serra, Marco, Mariani, Pascale, Descroix, Stéphanie, Sens, Pierre, Trepat, Xavier, Vignjevic, Danijela Matic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618488/
https://www.ncbi.nlm.nih.gov/pubmed/37907483
http://dx.doi.org/10.1038/s41467-023-42382-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618488/
https://www.ncbi.nlm.nih.gov/pubmed/37907483
http://dx.doi.org/10.1038/s41467-023-42382-4

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