Cargando…

Inflammation-related signature for prognostic prediction, tumor immune, genomic heterogeneity, and drug choices in prostate cancer: Integrated analysis of bulk and single-cell RNA-sequencing

BACKGROUND: Prostate cancer (PCa) ranks as the second most prevalent malignancy among males on a global scale. Accumulating evidence suggests that inflammation has an intricate relationship with tumorigenesis, tumor progression and tumor immune microenvironment. However, the overall impact of inflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Weian, Huang, Jiongduan, Wu, Jianjie, Wu, Chenglun, Ye, Fengxi, Li, Xiang, Lai, Wenjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618505/ https://www.ncbi.nlm.nih.gov/pubmed/37920511 http://dx.doi.org/10.1016/j.heliyon.2023.e21174

Ejemplares similares

Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer
por: Zhu, Weian, et al.
Publicado: (2023)

Integrated machine learning identifies epithelial cell marker genes for improving outcomes and immunotherapy in prostate cancer
por: Zhu, Weian, et al.
Publicado: (2023)

Single-cell and bulk RNA sequencing reveal cancer-associated fibroblast heterogeneity and a prognostic signature in prostate cancer
por: Liu, Wen, et al.
Publicado: (2023)

Single-Cell and Bulk RNA Sequencing Reveal Malignant Epithelial Cell Heterogeneity and Prognosis Signatures in Gastric Carcinoma
por: Huang, Zhihong, et al.
Publicado: (2022)

Integrated single-cell and bulk RNA sequencing in pancreatic cancer identifies disulfidptosis-associated molecular subtypes and prognostic signature
por: Wu, Yunhao, et al.
Publicado: (2023)

Integrating bulk and single-cell RNA sequencing data reveals the relationship between intratumor microbiome signature and host metabolic heterogeneity in breast cancer
por: Chen, Fangyue, et al.
Publicado: (2023)

Digital Protein Detection in Bulk Solutions
por: Beck, Sungjun, et al.
Publicado: (2022)

Physical exercise: bulking up neurogenesis in human adults
por: Lei, Xinjuan, et al.
Publicado: (2019)

Heterogeneous ice nucleation correlates with bulk-like interfacial water
por: Wu, Shuwang, et al.
Publicado: (2019)

The Prognostic Signature and Therapeutic Value of Phagocytic Regulatory Factors in Prostate Adenocarcinoma (PRAD)
por: Xin, Shiyong, et al.
Publicado: (2022)

Identification and Validation of a Prognostic 5-Protein Signature for Biochemical Recurrence Following Radical Prostatectomy for Prostate Cancer
por: Lv, Daojun, et al.
Publicado: (2021)

A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients
por: Salberg, Unn Beate, et al.
Publicado: (2022)

Collaborating single-cell and bulk RNA sequencing for comprehensive characterization of the intratumor heterogeneity and prognostic model development for bladder cancer
por: Wang, Jie, et al.
Publicado: (2023)

Integrated analysis of single-cell and bulk RNA-sequencing reveals tumor heterogeneity and a signature based on NK cell marker genes for predicting prognosis in hepatocellular carcinoma
por: Li, Shuo, et al.
Publicado: (2023)

Prognostic and Immune Implications of a Novel Pyroptosis-Related Five-Gene Signature in Breast Cancer
por: Zheng, Yuanyuan, et al.
Publicado: (2022)

Identification and Validation of FGF-Related Prognostic Signatures in Prostate Cancer
por: Ye, Yongkang, et al.
Publicado: (2023)

Metabolic heterogeneity signature of primary treatment-naïve prostate cancer
por: Lin, Dong, et al.
Publicado: (2017)

Combining bulk and single-cell RNA-sequencing data to develop an NK cell-related prognostic signature for hepatocellular carcinoma based on an integrated machine learning framework
por: Feng, Qian, et al.
Publicado: (2023)

Integration of bulk RNA sequencing data and single-cell RNA sequencing analysis on the heterogeneity in patients with colorectal cancer
por: Zhang, Jiawei, et al.
Publicado: (2023)

CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data
por: Abécassis, Judith, et al.
Publicado: (2021)

Integrated single-cell and bulk RNA sequencing analysis identifies a prognostic signature related to ferroptosis dependence in colorectal cancer
por: Xu, Xiaochen, et al.
Publicado: (2023)

Integration of single-cell and bulk RNA sequencing to establish a prognostic signature based on tumor-associated macrophages in colorectal cancer
por: Li, Hua, et al.
Publicado: (2023)

Identifying prognostic signatures in the microenvironment of prostate cancer
por: Lu, Guoliang, et al.
Publicado: (2021)

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils the Characteristics of the Immune Microenvironment and Prognosis Signature in Prostate Cancer
por: Wang, Ruisong, et al.
Publicado: (2022)

Ductile bulk metallic glass by controlling structural heterogeneities
por: Scudino, S., et al.
Publicado: (2018)

Strong and Ductile Electroplated Heterogeneous Bulk Nanostructured Nickel
por: Jiang, Yaoyao, et al.
Publicado: (2019)

Prognostic implication of heterogeneity and trajectory progression induced by enzalutamide in prostate cancer
por: Feng, Yuanfa, et al.
Publicado: (2023)

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma
por: Gong, Qiming, et al.
Publicado: (2023)

Identification of Transcriptional Heterogeneity and Construction of a Prognostic Model for Melanoma Based on Single-Cell and Bulk Transcriptome Analysis
por: Kang, Zijian, et al.
Publicado: (2022)

Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma
por: Wang, Tingjie, et al.
Publicado: (2022)

Integrated analysis of single-cell and Bulk RNA sequencing reveals a malignancy-related signature in lung adenocarcinoma
por: Wu, Mengxi, et al.
Publicado: (2023)

Combined Let-7a and H19 Signature: A Prognostic Index of Progression-Free Survival in Primary Breast Cancer Patients
por: Guo, Qiannan, et al.
Publicado: (2018)

Integrating single-cell RNA-seq and bulk RNA-seq to construct prognostic signatures to explore the role of glutamine metabolism in breast cancer
por: Pei, Shengbin, et al.
Publicado: (2023)

Integrated analysis of single-cell and bulk RNA-seq establishes a novel signature for prediction in gastric cancer
por: Wen, Fei, et al.
Publicado: (2023)

Bulk RKKY signatures of topological phase transition in silicene
por: Duan, Hou-Jian, et al.
Publicado: (2018)

Unveiling mitophagy-mediated molecular heterogeneity and development of a risk signature model for colorectal cancer by integrated scRNA-seq and bulk RNA-seq analysis
por: Gao, Han, et al.
Publicado: (2023)

Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits
por: Zimak, Jan, et al.
Publicado: (2021)

Delving into the Heterogeneity of Different Breast Cancer Subtypes and the Prognostic Models Utilizing scRNA-Seq and Bulk RNA-Seq
por: Xu, Jieyun, et al.
Publicado: (2022)

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
por: Wu, Xiaoqing, et al.
Publicado: (2023)

Bulk Perovskite Crystal Properties Determined by Heterogeneous Nucleation and Growth
por: Barua, Pranta, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_88ts9dkmj277dfirbqu5j1n4rv