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Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria

AIM: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria. MATERIALS AND METHODS: Records of 188 eyes, collected from 94 patients diagnosed with POA...

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Autores principales: Ezinne, Ngozika E, Kwarteng, Michael A, Ekemiri, Kingsley K, Iroanachi, Victoria I, Tagoh, Selassie, Ogbonna, Grace, Mashige, Khathutshelo P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618605/
https://www.ncbi.nlm.nih.gov/pubmed/37920378
http://dx.doi.org/10.5005/jp-journals-10078-1413
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author Ezinne, Ngozika E
Kwarteng, Michael A
Ekemiri, Kingsley K
Iroanachi, Victoria I
Tagoh, Selassie
Ogbonna, Grace
Mashige, Khathutshelo P
author_facet Ezinne, Ngozika E
Kwarteng, Michael A
Ekemiri, Kingsley K
Iroanachi, Victoria I
Tagoh, Selassie
Ogbonna, Grace
Mashige, Khathutshelo P
author_sort Ezinne, Ngozika E
collection PubMed
description AIM: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria. MATERIALS AND METHODS: Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed. RESULTS: The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (p = 0.02). Although CCT decreased with age (r = −0.28, p = 0.005), there was no such link between IOP and CCT (r = 0.09, p = 0.38). CONCLUSION: Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised. HOW TO CITE THIS ARTICLE: Ezinne NE, Kwarteng MA, Ekemiri KK, et al. Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria. J Curr Glaucoma Pract 2023;17(3):113–117.
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spelling pubmed-106186052023-11-02 Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria Ezinne, Ngozika E Kwarteng, Michael A Ekemiri, Kingsley K Iroanachi, Victoria I Tagoh, Selassie Ogbonna, Grace Mashige, Khathutshelo P J Curr Glaucoma Pract Original Research AIM: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria. MATERIALS AND METHODS: Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed. RESULTS: The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (p = 0.02). Although CCT decreased with age (r = −0.28, p = 0.005), there was no such link between IOP and CCT (r = 0.09, p = 0.38). CONCLUSION: Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised. HOW TO CITE THIS ARTICLE: Ezinne NE, Kwarteng MA, Ekemiri KK, et al. Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria. J Curr Glaucoma Pract 2023;17(3):113–117. Jaypee Brothers Medical Publishers 2023 /pmc/articles/PMC10618605/ /pubmed/37920378 http://dx.doi.org/10.5005/jp-journals-10078-1413 Text en Copyright © 2023; The Author(s). https://creativecommons.org/licenses/by-nc/4.0/© The Author(s). 2023 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Research
Ezinne, Ngozika E
Kwarteng, Michael A
Ekemiri, Kingsley K
Iroanachi, Victoria I
Tagoh, Selassie
Ogbonna, Grace
Mashige, Khathutshelo P
Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title_full Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title_fullStr Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title_full_unstemmed Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title_short Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria
title_sort clinical profile of primary open-angle glaucoma patients at an eye center in nigeria
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618605/
https://www.ncbi.nlm.nih.gov/pubmed/37920378
http://dx.doi.org/10.5005/jp-journals-10078-1413
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