Polymorphisms in Cyclooxygenase, Lipoxygenase, and TP53 Genes Predict Colorectal Polyp Risk Reduction by Aspirin in the seAFOod Polyp Prevention Trial

Aspirin and eicosapentaenoic acid (EPA) reduce colorectal adenomatous polyp risk and affect synthesis of oxylipins including prostaglandin E(2). We investigated whether 35 SNPs in oxylipin metabolism genes such as cyclooxygenase (PTGS) and lipoxygenase (ALOX), as well as 7 SNPs already associated wi...

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Detalles Bibliográficos
Autores principales: Davies, John R., Mell, Tracey, Fuller, Harriett, Harland, Mark, Saleh, Rasha N.M., Race, Amanda D., Rees, Colin J., Brown, Louise C., Loadman, Paul M., Downing, Amy, Minihane, Anne Marie, Williams, Elizabeth A., Hull, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618644/
https://www.ncbi.nlm.nih.gov/pubmed/37756582
http://dx.doi.org/10.1158/1940-6207.CAPR-23-0111

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