Cargando…

ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis

PURPOSE: Limited effective treatments are currently available for central nervous system (CNS) metastasis (CM). This is largely driven by the inability of current therapeutics to penetrate the blood brain barrier (BBB) and the lack of preclinical models for testing new therapies. Here we study the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Tew, Ben Yi, Kalfa, Alex J., Yang, Zeyi, Hurth, Kyle M., Simon, Thomas, Abnoosian, Eric, Durant, Stephen T., Hamerlik, Petra, Salhia, Bodour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618650/
https://www.ncbi.nlm.nih.gov/pubmed/37585496
http://dx.doi.org/10.1158/1078-0432.CCR-23-0290