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FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons

MicroRNAs (miRNAs) modulate mRNA expression, and their deregulation contributes to various diseases including amyotrophic lateral sclerosis (ALS). As fused in sarcoma (FUS) is a causal gene for ALS and regulates biogenesis of miRNAs, we systematically analyzed the miRNA repertoires in spinal cords a...

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Detalles Bibliográficos
Autores principales:	Ho, Wan Yun, Chak, Li-Ling, Hor, Jin-Hui, Liu, Fujia, Diaz-Garcia, Sandra, Chang, Jer-Cherng, Sanford, Emma, Rodriguez, Maria J., Alagappan, Durgadevi, Lim, Su Min, Cho, Yik-Lam, Shimizu, Yuji, Sun, Alfred Xuyang, Tyan, Sheue-Houy, Koo, Edward, Kim, Seung Hyun, Ravits, John, Ng, Shi-Yan, Okamura, Katsutomo, Ling, Shuo-Chien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618709/ https://www.ncbi.nlm.nih.gov/pubmed/37920668 http://dx.doi.org/10.1016/j.isci.2023.108152

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