Matrix Stiffness Triggers Lipid Metabolic Cross-talk between Tumor and Stromal Cells to Mediate Bevacizumab Resistance in Colorectal Cancer Liver Metastases

Bevacizumab is an anti-VEGF monoclonal antibody that plays an important role in the combination treatment of advanced colorectal cancer. However, resistance remains a major hurdle limiting bevacizumab efficacy, highlighting the importance of identifying a mechanism of antiangiogenic therapy resistan...

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Detalles Bibliográficos
Autores principales: Zheng, Yannan, Zhou, Rui, Cai, Jianan, Yang, Nanyan, Wen, Zhaowei, Zhang, Zhihua, Sun, Huiying, Huang, Genjie, Guan, Yijin, Huang, Na, Shi, Min, Liao, Yulin, Bin, Jianping, Liao, Wangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cancer Metabolism and Molecular Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618741/
https://www.ncbi.nlm.nih.gov/pubmed/37610655
http://dx.doi.org/10.1158/0008-5472.CAN-23-0025

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