Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer

Transposable elements hold regulatory functions that impact cell fate determination by controlling gene expression. However, little is known about the transcriptional machinery engaged at transposable elements in pluripotent and mature versus oncogenic cell states. Through positional analysis over r...

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Detalles Bibliográficos
Autores principales: Grillo, Giacomo, Keshavarzian, Tina, Linder, Simon, Arlidge, Christopher, Mout, Lisanne, Nand, Ankita, Teng, Mona, Qamra, Aditi, Zhou, Stanley, Kron, Ken J., Murison, Alex, Hawley, James R., Fraser, Michael, van der Kwast, Theodorus H., Raj, Ganesh V., He, Housheng Hansen, Zwart, Wilbert, Lupien, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618745/
https://www.ncbi.nlm.nih.gov/pubmed/37694973
http://dx.doi.org/10.1158/2159-8290.CD-23-0331

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