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Investigating cannabinoids as P2X purinoreceptor 4 ligands by using surface plasmon resonance and computational docking

P2X purinoceptor 4 (P2X4) is an ATP-gated ion channel receptor with diverse neurophysiological functions, and P2X4 modulators hold promise as potential therapeutics for neuropathic pain, neuroinflammation, and neurodegenerative diseases. While several cannabinoids have been reported as modulators of...

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Detalles Bibliográficos
Autores principales: Puopolo, Tess, Cai, Ang, Liu, Chang, Ma, Hang, Seeram, Navindra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618793/
https://www.ncbi.nlm.nih.gov/pubmed/37920520
http://dx.doi.org/10.1016/j.heliyon.2023.e21265

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