Cargando…
Investigating cannabinoids as P2X purinoreceptor 4 ligands by using surface plasmon resonance and computational docking
P2X purinoceptor 4 (P2X4) is an ATP-gated ion channel receptor with diverse neurophysiological functions, and P2X4 modulators hold promise as potential therapeutics for neuropathic pain, neuroinflammation, and neurodegenerative diseases. While several cannabinoids have been reported as modulators of...
Autores principales: | Puopolo, Tess, Cai, Ang, Liu, Chang, Ma, Hang, Seeram, Navindra P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618793/ https://www.ncbi.nlm.nih.gov/pubmed/37920520 http://dx.doi.org/10.1016/j.heliyon.2023.e21265 |
Ejemplares similares
-
Identification of SARS-CoV-2 Main Protease Inhibitors from a Library of Minor Cannabinoids by Biochemical Inhibition Assay and Surface Plasmon Resonance Characterized Binding Affinity
por: Liu, Chang, et al.
Publicado: (2022) -
Establishment of Human PD-1/PD-L1 Blockade Assay Based on Surface Plasmon Resonance (SPR) Biosensor
por: Puopolo, Tess, et al.
Publicado: (2023) -
Cannflavins A and B with Anti-Ferroptosis, Anti-Glycation, and Antioxidant Activities Protect Human Keratinocytes in a Cell Death Model with Erastin and Reactive Carbonyl Species
por: Li, Huifang, et al.
Publicado: (2023) -
Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating
por: Rokic, Milos B., et al.
Publicado: (2014) -
Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase
por: Puopolo, Tess, et al.
Publicado: (2022)