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p16(Ink4a), a marker of cellular senescence, is associated with renal disease in the B6.NZMSle1/Sle2/Sle3 mouse model of lupus
OBJECTIVES: Despite treatment, one-third of patients with lupus nephritis (LN) show a decline in renal function. Prognostic markers of poor outcome as well as novel therapeutic targets are therefore highly sought. We showed that p16(INK4a), a marker of cellular senescence, is observed in baseline ki...
Autores principales: | Tilman, Gaëlle, Dupré, Emilie, Watteyne, Laura, Baert, Charlotte Anne, Nolf, Delphine, Benhaddi, Fatima, Lambert, Fanny, Daumerie, Aurélie, Bouzin, Caroline, Lucas, Sophie, Limaye, Nisha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619045/ https://www.ncbi.nlm.nih.gov/pubmed/37899089 http://dx.doi.org/10.1136/lupus-2023-001010 |
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