Cargando…

Structure-informed clustering for population stratification in association studies

BACKGROUND: Identifying variants associated with complex traits is a challenging task in genetic association studies due to linkage disequilibrium (LD) between genetic variants and population stratification, unrelated to the disease risk. Existing methods of population structure correction use princ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bose, Aritra, Burch, Myson, Chowdhury, Agniva, Paschou, Peristera, Drineas, Petros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619291/ https://www.ncbi.nlm.nih.gov/pubmed/37907836 http://dx.doi.org/10.1186/s12859-023-05511-w

Ejemplares similares

Integrating Linguistics, Social Structure, and Geography to Model Genetic Diversity within India
por: Bose, Aritra, et al.
Publicado: (2021)

Inferring Geographic Coordinates of Origin for Europeans Using Small Panels of Ancestry Informative Markers
por: Drineas, Petros, et al.
Publicado: (2010)

Reconstructing SNP allele and genotype frequencies from GWAS summary statistics
por: Yang, Zhiyu, et al.
Publicado: (2022)

Tracing Cattle Breeds with Principal Components Analysis Ancestry Informative SNPs
por: Lewis, Jamey, et al.
Publicado: (2011)

Can polygenic risk scores help explain disease prevalence differences around the world? A worldwide investigation
por: Jain, Pritesh R., et al.
Publicado: (2023)

PCA-Correlated SNPs for Structure Identification in Worldwide Human Populations
por: Paschou, Peristera, et al.
Publicado: (2007)

Variant Ranker: a web-tool to rank genomic data according to functional significance
por: Alexander, John, et al.
Publicado: (2017)

Tracing Sub-Structure in the European American Population with PCA-Informative Markers
por: Paschou, Peristera, et al.
Publicado: (2008)

Multiomic approach and Mendelian randomization analysis identify causal associations between blood biomarkers and subcortical brain structure volumes
por: Jain, Pritesh, et al.
Publicado: (2023)

Genetics of the peloponnesean populations and the theory of extinction of the medieval peloponnesean Greeks
por: Stamatoyannopoulos, George, et al.
Publicado: (2017)

A European population in Minoan Bronze Age Crete
por: Hughey, Jeffery R., et al.
Publicado: (2013)

Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder Provides Support for a Shared Genetic Basis
por: Tsetsos, Fotis, et al.
Publicado: (2016)

Genetic history of the population of Crete
por: Drineas, Petros, et al.
Publicado: (2019)

Candidate Genes and Pathways Associated with Gilles de la Tourette Syndrome—Where Are We?
por: Levy, Amanda M., et al.
Publicado: (2021)

Editorial: The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues through Large-Scale Collaborative Projects
por: Paschou, Peristera, et al.
Publicado: (2017)

A Brief History of the European Society for the Study of Tourette Syndrome
por: Rickards, Hugh, et al.
Publicado: (2013)

PheWAS and cross-disorder analysis reveal genetic architecture, pleiotropic loci and phenotypic correlations across 11 autoimmune disorders
por: Topaloudi, Apostolia, et al.
Publicado: (2023)

Semi-supervised spectral clustering with application to detect population stratification
por: Liu, Binghui, et al.
Publicado: (2013)

Constructing Compact Signatures for Individual Fingerprinting of Brain Connectomes
por: Ravindra, Vikram, et al.
Publicado: (2021)

Population Structure, Stratification, and Introgression of Human Structural Variation
por: Almarri, Mohamed A., et al.
Publicado: (2020)

Population stratification and genetic association studies in South Asia
por: Bittles, Alan H
Publicado: (2005)

Targeted Re-Sequencing Approach of Candidate Genes Implicates Rare Potentially Functional Variants in Tourette Syndrome Etiology
por: Alexander, John, et al.
Publicado: (2016)

Population structure and pharmacogenomic risk stratification in the United States
por: Nagar, Shashwat Deepali, et al.
Publicado: (2020)

Canine Population Structure: Assessment and Impact of Intra-Breed Stratification on SNP-Based Association Studies
por: Quignon, Pascale, et al.
Publicado: (2007)

Comparison of Population-Based Association Study Methods Correcting for Population Stratification
por: Zhang, Feng, et al.
Publicado: (2008)

Handbook of big data
por: Bühlmann, Peter, et al.
Publicado: (2016)

The Genetic Etiology of Tourette Syndrome: Large-Scale Collaborative Efforts on the Precipice of Discovery
por: Georgitsi, Marianthi, et al.
Publicado: (2016)

Correction of Population Stratification in Large Multi-Ethnic Association Studies
por: Serre, David, et al.
Publicado: (2008)

Robust methods for population stratification in genome wide association studies
por: Liu, Li, et al.
Publicado: (2013)

Controlling for human population stratification in rare variant association studies
por: Bouaziz, Matthieu, et al.
Publicado: (2021)

Impact of Population Stratification on Family-Based Association in an Admixed Population
por: Mersha, T. B., et al.
Publicado: (2015)

Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies
por: Hao, Ke, et al.
Publicado: (2010)

Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification
por: Balluff, Benjamin, et al.
Publicado: (2019)

Optimal stratification in outcome prediction using baseline information
por: Yong, Florence H., et al.
Publicado: (2016)

Oxidative Stress Genes in Diabetes Mellitus Type 2: Association with Diabetic Kidney Disease
por: Roumeliotis, Athanasios, et al.
Publicado: (2021)

The Relationship between Burden and Depression in Spouses of Chronic Kidney Disease Patients
por: Paschou, Athina, et al.
Publicado: (2018)

Zgli: A Pipeline for Clustering by Compression with Application to Patient Stratification in Spondyloarthritis
por: Azevedo, Diogo, et al.
Publicado: (2023)

New clusters of serum electrolytes aid in stratification of diabetes and metabolic risk
por: Hou, Yanan, et al.
Publicado: (2021)

Stratification of COPD patients towards personalized medicine: reproduction and formation of clusters
por: van Zelst, Cathelijne M., et al.
Publicado: (2022)

Time-Rescaling of Dirac Dynamics: Shortcuts to Adiabaticity in Ion Traps and Weyl Semimetals
por: Roychowdhury, Agniva, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ii996uo0bt3m5vb6u52hud406r