Biological and therapeutic implications of RKIP in Gastrointestinal Stromal Tumor (GIST): an integrated transcriptomic and proteomic analysis

BACKGROUND: Gastrointestinal stromal tumors (GIST) represent a significant clinical challenge due to their metastatic potential and limited treatment options. Raf kinase inhibitor protein (RKIP), a suppressor of the MAPK signaling pathway, is downregulated in various cancers and acts as a metastasis...

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Detalles Bibliográficos
Autores principales: Campanella, Nathália Cristina, Gomes, Izabela Natalia Faria, Alves, Ana Laura Vieira, Leal, Leticia Ferro, Evangelista, Adriane Feijó, Rosa, Marcela Nunes, Melendez, Matias Eliseo, Silva, Viviane Aline Oliveira, Dias, Richard Lucas Konichi, Abrahão-Machado, Lucas Faria, Santana, Iara, Martinho, Olga, Guimarães, Denise Peixoto, Faça, Vitor Marcel, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619323/
https://www.ncbi.nlm.nih.gov/pubmed/37907993
http://dx.doi.org/10.1186/s12935-023-03102-6

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