Cocrystallization of ubiquitin–deubiquitinase complexes through disulfide linkage

Structural characterization of the recognition of ubiquitin (Ub) by deubiquitin­ases (DUBs) has largely relied on covalent complexation of the DUB through its catalytic cysteine with a Ub C-terminal electrophile. The Ub electrophiles are accessed through intein chemistry in conjunction with chemical...

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Detalles Bibliográficos
Autores principales: Negron Teron, Kristos I., Das, Chittaranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619426/
https://www.ncbi.nlm.nih.gov/pubmed/37877948
http://dx.doi.org/10.1107/S2059798323008501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619426/
https://www.ncbi.nlm.nih.gov/pubmed/37877948
http://dx.doi.org/10.1107/S2059798323008501

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