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Factor-inhibiting HIF (FIH) promotes lung cancer progression

Factor-inhibiting HIF (FIH) is an asparagine hydroxylase that acts on hypoxia-inducible factors (HIFs) to control cellular adaptation to hypoxia. FIH is expressed in several tumor types, but its impact in tumor progression remains largely unexplored. We observed that FIH was expressed on human lung...

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Detalles Bibliográficos
Autores principales: García-del Río, Ana, Prieto-Fernández, Endika, Egia-Mendikute, Leire, Antoñana-Vildosola, Asier, Jimenez-Lasheras, Borja, Lee, So Young, Barreira-Manrique, Adrián, Zanetti, Samanta Romina, de Blas, Ander, Velasco-Beltrán, Paloma, Bosch, Alexandre, Aransay, Ana M., Palazon, Asis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619494/
https://www.ncbi.nlm.nih.gov/pubmed/37707961
http://dx.doi.org/10.1172/jci.insight.167394

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