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Isradipine therapy in Cacna1d(Ile772Met/+) mice ameliorates primary aldosteronism and neurologic abnormalities

Somatic gain-of-function mutations in the L-type calcium channel Ca(V)1.3 (CACNA1D gene) cause adrenal aldosterone-producing adenomas and micronodules. De novo germline mutations are found in a syndrome of primary aldosteronism, seizures, and neurologic abnormalities (PASNA) as well as in autism spe...

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Detalles Bibliográficos
Autores principales:	Stölting, Gabriel, Dinh, Hoang An, Volkert, Marina, Hellmig, Nicole, Schewe, Julia, Hennicke, Luise, Seidel, Eric, Oberacher, Herbert, Zhang, Junhui, Lifton, Richard P., Urban, Iris, Long, Melissa, Rivalan, Marion, Nottoli, Timothy, Scholl, Ute I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619505/ https://www.ncbi.nlm.nih.gov/pubmed/37698934 http://dx.doi.org/10.1172/jci.insight.162468

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