Inhibition of retinoic acid signaling in proximal tubular epithelial cells protects against acute kidney injury

Retinoic acid receptor (RAR) signaling is essential for mammalian kidney development but, in the adult kidney, is restricted to occasional collecting duct epithelial cells. We now show that there is widespread reactivation of RAR signaling in proximal tubular epithelial cells (PTECs) in human sepsis...

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Detalles Bibliográficos
Autores principales: Yang, Min, Lopez, Lauren N., Brewer, Maya, Delgado, Rachel, Menshikh, Anna, Clouthier, Kelly, Zhu, Yuantee, Vanichapol, Thitinee, Yang, Haichun, Harris, Raymond C., Gewin, Leslie, Brooks, Craig R., Davidson, Alan J., de Caestecker, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619506/
https://www.ncbi.nlm.nih.gov/pubmed/37698919
http://dx.doi.org/10.1172/jci.insight.173144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619506/
https://www.ncbi.nlm.nih.gov/pubmed/37698919
http://dx.doi.org/10.1172/jci.insight.173144

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