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Regulatory factor X1 induces macrophage M1 polarization by promoting DNA demethylation in autoimmune inflammation

Abnormal macrophage polarization is generally present in autoimmune diseases. Overwhelming M1 macrophage activation promotes the continuous progression of inflammation, which is one of the reasons for the development of autoimmune diseases. However, the underlying mechanism is still unclear. Here we...

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Detalles Bibliográficos
Autores principales: Yang, Shuang, Du, Pei, Cui, Haobo, Zheng, Meiling, He, Wei, Gao, Xiaofei, Hu, Zhi, Jia, Sujie, Lu, Qianjin, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619507/
https://www.ncbi.nlm.nih.gov/pubmed/37733446
http://dx.doi.org/10.1172/jci.insight.165546