Cargando…

Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases

BACKGROUND: Exposure to ionizing radiations and other hazardous agents such as anesthetic gases pose serious risks to the health of healthcare workers. This study aimed to evaluate the changes in blood and biochemical parameters of the operating room staff exposed to ionizing radiations and remnants...

Descripción completa

Detalles Bibliográficos
Autores principales: Rezaei, Bareza, Salehi Zahabi, Saleh, darvishi, Fatemeh, Salehi, Amir, Hemmatpour, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619581/
https://www.ncbi.nlm.nih.gov/pubmed/37920652
http://dx.doi.org/10.1097/MS9.0000000000001372
_version_ 1785130015983140864
author Rezaei, Bareza
Salehi Zahabi, Saleh
darvishi, Fatemeh
Salehi, Amir
Hemmatpour, Behzad
author_facet Rezaei, Bareza
Salehi Zahabi, Saleh
darvishi, Fatemeh
Salehi, Amir
Hemmatpour, Behzad
author_sort Rezaei, Bareza
collection PubMed
description BACKGROUND: Exposure to ionizing radiations and other hazardous agents such as anesthetic gases pose serious risks to the health of healthcare workers. This study aimed to evaluate the changes in blood and biochemical parameters of the operating room staff exposed to ionizing radiations and remnants of anesthetic gas. METHODS: This cross-sectional study was performed at (Ayatollah Taleghani Hospital). The control group was selected from different parts of the hospital that were not exposed to ionizing radiations and anesthetics, including the office, services, and treatment. The case group included all operating room personnel. Hematopoietic parameters such as complete blood count and WBC differential, and parameters of liver function such as serum activity of liver enzymes (ALT, AST, ALP, LDH) and serum bilirubin levels, fasting blood sugar, serum lipid profile, level of vitamin D and magnesium were measured for the exposed and referent subjects. Additionally, a checklist was used to gather data regarding the occupational variables and medical histories of the studied subjects. RESULTS: The mean values of Hb, Hct, Vitamin D, and MCHC, as well as the RBC count, were significantly lower in the exposed individuals than in the referent subjects. In contrast, the proportion of smokers was significantly higher in the exposed group than in the referent group. No significant differences were noted between exposed and unexposed groups as far as other parameters were concerned. However, no significant differences were noted between the case and control groups as far as other measured parameters were concerned. Likewise, no significant differences were noted between exposed and referent groups as far as blood types, history of underlying diseases, work history, working hours per month, number of morning and evening shift hours, type of diet, consumption of a high-fat diet a day before blood sampling, X-ray in the recent year, history of radiotherapy, and therapeutic agents use was concerned. CONCLUSIONS: Exposure of operating room staff to ionizing radiations and waste anesthetics gases is associated with subtle, subclinical prepathologic decreases in some hematopoietic parameters such as hemoglobin, hematocrit and MCHC levels, RBC count as well as vitamin D levels.
format Online
Article
Text
id pubmed-10619581
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-106195812023-11-02 Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases Rezaei, Bareza Salehi Zahabi, Saleh darvishi, Fatemeh Salehi, Amir Hemmatpour, Behzad Ann Med Surg (Lond) Original Research BACKGROUND: Exposure to ionizing radiations and other hazardous agents such as anesthetic gases pose serious risks to the health of healthcare workers. This study aimed to evaluate the changes in blood and biochemical parameters of the operating room staff exposed to ionizing radiations and remnants of anesthetic gas. METHODS: This cross-sectional study was performed at (Ayatollah Taleghani Hospital). The control group was selected from different parts of the hospital that were not exposed to ionizing radiations and anesthetics, including the office, services, and treatment. The case group included all operating room personnel. Hematopoietic parameters such as complete blood count and WBC differential, and parameters of liver function such as serum activity of liver enzymes (ALT, AST, ALP, LDH) and serum bilirubin levels, fasting blood sugar, serum lipid profile, level of vitamin D and magnesium were measured for the exposed and referent subjects. Additionally, a checklist was used to gather data regarding the occupational variables and medical histories of the studied subjects. RESULTS: The mean values of Hb, Hct, Vitamin D, and MCHC, as well as the RBC count, were significantly lower in the exposed individuals than in the referent subjects. In contrast, the proportion of smokers was significantly higher in the exposed group than in the referent group. No significant differences were noted between exposed and unexposed groups as far as other parameters were concerned. However, no significant differences were noted between the case and control groups as far as other measured parameters were concerned. Likewise, no significant differences were noted between exposed and referent groups as far as blood types, history of underlying diseases, work history, working hours per month, number of morning and evening shift hours, type of diet, consumption of a high-fat diet a day before blood sampling, X-ray in the recent year, history of radiotherapy, and therapeutic agents use was concerned. CONCLUSIONS: Exposure of operating room staff to ionizing radiations and waste anesthetics gases is associated with subtle, subclinical prepathologic decreases in some hematopoietic parameters such as hemoglobin, hematocrit and MCHC levels, RBC count as well as vitamin D levels. Lippincott Williams & Wilkins 2023-10-02 /pmc/articles/PMC10619581/ /pubmed/37920652 http://dx.doi.org/10.1097/MS9.0000000000001372 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Research
Rezaei, Bareza
Salehi Zahabi, Saleh
darvishi, Fatemeh
Salehi, Amir
Hemmatpour, Behzad
Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title_full Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title_fullStr Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title_full_unstemmed Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title_short Evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
title_sort evaluation of biochemical parameters in operating room staff exposed to radiation and anesthetic gases
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619581/
https://www.ncbi.nlm.nih.gov/pubmed/37920652
http://dx.doi.org/10.1097/MS9.0000000000001372
work_keys_str_mv AT rezaeibareza evaluationofbiochemicalparametersinoperatingroomstaffexposedtoradiationandanestheticgases
AT salehizahabisaleh evaluationofbiochemicalparametersinoperatingroomstaffexposedtoradiationandanestheticgases
AT darvishifatemeh evaluationofbiochemicalparametersinoperatingroomstaffexposedtoradiationandanestheticgases
AT salehiamir evaluationofbiochemicalparametersinoperatingroomstaffexposedtoradiationandanestheticgases
AT hemmatpourbehzad evaluationofbiochemicalparametersinoperatingroomstaffexposedtoradiationandanestheticgases