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Effect of cyclic substituents on the anti-cancer activity and DNA interaction of ruthenium(II) bis-phenanthroline dipyridoquinoline

Introduction: Ruthenium(II) complexes have emerged recently as candidates for anti-cancer therapy, where activity is related to lipohilicity, cellular localization, and specific interactions with biomolecules. Methods: In this work, two novel complexes were synthesized and are reported based on the...

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Detalles Bibliográficos
Autores principales: Nyong-Bassey, Etubonesi E., Hicks, Andrew L., Bergin, Poppy, Tuite, Eimer M., Kozhevnikov, Valery, Veuger, Stephany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619691/
https://www.ncbi.nlm.nih.gov/pubmed/37920709
http://dx.doi.org/10.3389/fmolb.2023.1252285