Silibinin Prevents TGFβ-Induced EMT of RPE in Proliferative Vitreoretinopathy by Inhibiting Stat3 and Smad3 Phosphorylation

PURPOSE: The purpose of this study was to investigate the effects of silibinin on epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) and proliferative vitreoretinopathy (PVR) formation, as well as its underlying molecular mechanism. METHODS: Cellular morphological change and...

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Detalles Bibliográficos
Autores principales: Ma, Xinqi, Xie, Yiyu, Gong, Yajun, Hu, Chuxuan, Qiu, Kairui, Yang, Yao, Shen, Huangxuan, Zhou, Xiaolai, Long, Chongde, Lin, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619698/
https://www.ncbi.nlm.nih.gov/pubmed/37906058
http://dx.doi.org/10.1167/iovs.64.13.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619698/
https://www.ncbi.nlm.nih.gov/pubmed/37906058
http://dx.doi.org/10.1167/iovs.64.13.47

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