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Bioassays guided isolation of berberine from Berberis lycium and its neuroprotective role in aluminium chloride induced rat model of Alzheimer’s disease combined with insilico molecular docking

OBJECTIVE: Berberis lycium is an indigenous plant of Pakistan that is known for its medicinal properties. In the current study, we investigated the anti-Alzheimer’s effect of berberine isolated from Berberis lycium. METHODS: Root extract of B. lycium was subjected to acetylcholinesterase inhibition...

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Detalles Bibliográficos
Autores principales: Ismail, Hammad, Khalid, Dania, Waseem, Durdana, Ijaz, Muhammad Umar, Dilshad, Erum, Haq, Ihsan-ul, Bhatti, Muhammad Zeeshan, Anwaar, Sadaf, Ahmed, Madiha, Saleem, Samreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619822/
https://www.ncbi.nlm.nih.gov/pubmed/37910530
http://dx.doi.org/10.1371/journal.pone.0286349