STAT1 deficiency underlies a proinflammatory imprint of naive CD4(+) T cells in spondyloarthritis

INTRODUCTION: In spondyloarthritis (SpA), an increased type 3 immune response, including T helper cells (Th) 17 excess, is observed in both human and SpA animal models, such as the HLA-B27/human β2-microglobulin transgenic rat (B27-rat). METHODS: To investigate this unexplained Th17-biased different...

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Detalles Bibliográficos
Autores principales: Cherqaoui, Bilade, Crémazy, Frédéric, Lauraine, Marc, Shammas, Ghazal, Said-Nahal, Roula, Mambu Mambueni, Hendrick, Costantino, Félicie, Fourmont, Marine, Hulot, Audrey, Garchon, Henri-Jean, Glatigny, Simon, Araujo, Luiza M., Breban, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619905/
https://www.ncbi.nlm.nih.gov/pubmed/37920469
http://dx.doi.org/10.3389/fimmu.2023.1227281

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