Neural adaption in midbrain GABAergic cells contributes to high-fat diet–induced obesity

Overeating disorders largely contribute to worldwide incidences of obesity. Available treatments are limited. Here, we discovered that long-term chemogenetic activation of ventrolateral periaqueductal gray (vlPAG) GABAergic cells rescue obesity of high-fat diet–induced obesity (DIO) mice. This was a...

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Detalles Bibliográficos
Autores principales: Wang, Xiaomeng, Wu, Xiaotong, Wu, Hao, Xiao, Hanyang, Hao, Sijia, Wang, Bingwei, Li, Chen, Bleymehl, Katherin, Kauschke, Stefan G., Mack, Volker, Ferger, Boris, Klein, Holger, Zheng, Ruimao, Duan, Shumin, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619925/
https://www.ncbi.nlm.nih.gov/pubmed/37910621
http://dx.doi.org/10.1126/sciadv.adh2884

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