The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson’s disease

Parkinson’s disease (PD) is characterized by the pathologic aggregation and prion-like propagation of α-synuclein (α-syn). Emerging evidence shows that fungal infections increase the incidence of PD. However, the molecular mechanisms by which fungi promote the onset of PD are poorly understood. Here...

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Detalles Bibliográficos
Autores principales: Meng, Lanxia, Liu, Congcong, Li, Yiming, Chen, Guiqin, Xiong, Min, Yu, Ting, Pan, Lina, Zhang, Xingyu, Zhou, Lingyan, Guo, Tao, Yuan, Xin, Liu, Chaoyang, Zhang, Zhaohui, Zhang, Zhentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619926/
https://www.ncbi.nlm.nih.gov/pubmed/37910610
http://dx.doi.org/10.1126/sciadv.adj1092

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