UNC-49 is a redox-sensitive GABA(A) receptor that regulates the mitochondrial unfolded protein response cell nonautonomously

The γ-aminobutyric acid–mediated (GABAergic) system participates in many aspects of organismal physiology and disease, including proteostasis, neuronal dysfunction, and life-span extension. Many of these phenotypes are also regulated by reactive oxygen species (ROS), but the redox mechanisms linking...

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Detalles Bibliográficos
Autores principales: Pohl, Franziska, Germann, Allison L., Mao, Jack, Hou, Sydney, Bakare, Bayode, Kong Thoo Lin, Paul, Yates, Kyari, Nonet, Michael L., Akk, Gustav, Kornfeld, Kerry, Held, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619936/
https://www.ncbi.nlm.nih.gov/pubmed/37910615
http://dx.doi.org/10.1126/sciadv.adh2584

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