Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells

Children with severe acute malnutrition (SAM) have high infectious mortality and morbidity, implicating defects in their immune defenses. We hypothesized that circulating innate immune cells from children (0 to 59 months) hospitalized with SAM in Zambia and Zimbabwe (n = 141) have distinct capacity...

Descripción completa

Detalles Bibliográficos
Autores principales: Phiri, Tracy N., Mutasa, Kuda, Rukobo, Sandra, Govha, Margaret, Mushayanembwa, Patience, Mwakamui, Simutanyi, Haider, Tafhima, Zyambo, Kanekwa, Dumbura, Cherlynn, Tome, Joice, Runodamoto, Thompson, Chidamba, Leah, Majo, Florence D., Ngosa, Deophine, Chandwe, Kanta, Kapoma, Chanda, Mwapenya, Benjamin, Mufukari, Wadzanai, Sturgeon, Jonathan P., Robertson, Ruairi C., Smuk, Melanie, Ntozini, Robert, Nathoo, Kusum, Amadi, Beatrice, Kelly, Paul, Bwakura-Dangarembizi, Mutsa, Prendergast, Andrew J., Bourke, Claire D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619937/
https://www.ncbi.nlm.nih.gov/pubmed/37910623
http://dx.doi.org/10.1126/sciadv.adh2284

Ejemplares similares

Ejemplares similares